CASE BACKGROUND
Situation
- Client is focused on the discovery and development of precision medicines for difficult-to-treat cancers
- The target disease is rare. About 8,000 people in the United States are diagnosed with it each year
Challenges
- Identifying HCPs and treatment centers with potential patients for clinical trials is a lengthy process
- Client sought to explore approaches to leverage real-world data to improve and accelerate the clinical trial recruitment process
Key Business questions
- What is the size of the target clinical trial patient pool
- Where are those patients located
- Which Clinicians are treating target patients?
- How do we prioritize Clinicians to contact for clinical trial participation?
APPROACH
ANALYZE
Identified & Segmented Potential Patients:
- With client input, collaboratively define the appropriate patient inclusion and exclusion criteria using the clinical trial protocol as a basis to create the patient cohort
- Iterative data analysis to identify and segment patients who meet clinical trial criteria
Assess
Connected Clinicians to Anonymized Patients:
- Map patients back to Clinicians who were treating or referring them with “specific” diagnoses
Segmented and Mapped Clinicians:
- Map connections between those treaters and current client trialists based on patients in common
Action
Assessed Clinicians Based on Connections to Current Trialists and Patients in Common:
- Number of qualifying patients
- Number of qualifying patients shared with client investigators
- Recency and frequency of qualifying patient visits
- HCP specialty
- Proximity to existing client sites for company outreach
OUTCOME
Identified High Potential Clinical Trialists
- Found over 200 Clinicians with patients meeting clinical trial protocol criteria
Prioritized Recruitment of Target Patients
- Mapped patients back to Clinicians who were treating or referring them with “specific” diagnoses
- Mapped connections between those treaters and current client trialists based on patients in common
Accelerated the Clinical Trial Recruitment Process
Prioritized potential new investigators for engagement based on:
- Number of qualifying patients
- Number of qualifying patients shared with
client investigators - Recency and frequency of qualifying patient visits
- HCP specialty
- Proximity to current trial sites for company outreach
